Related Experiment Video
Updated: Dec 6, 2025

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
Published on: May 26, 2023
Firm Cutaneous Nodule on the Dorsal Hand: A Case Report on Fibroblastic Rheumatism
Reba Suri1,2, Martin J Azzam3,2, Michael R Heaphy4
1Dermatology, University of Kansas Medical Center, Kansas City, USA.
Abstract:
Fibroblastic rheumatism (FR) is a rare dermatoarthropathy of unknown etiology. It is characterized by the onset of firm cutaneous nodules in patients with rheumatologic symptoms such as arthralgias or symmetric polyarthritis. Clinicopathologic correlation is critical in establishing the diagnosis, as the clinical manifestations can resemble other fibrosing conditions. In this report, we review the clinical and histologic features of FR, as well as conditions similar to those of the case we present, with dermatologic and rheumatologic manifestations. As part of our research, a PubMed search of the following terms was performed: "arthralgia, arthritis, arthropathy, cutaneous, disease, fibroblast, fibrosing, nodule, rheumatism, and rheumatology". This report discusses a unique case of FR diagnosed in a 37-year-old man with a single cutaneous nodule.
Related Concept Videos
Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Reticular Dermis
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Rheumatic Heart Disease I: Introduction
Introduction to Fibroblasts

