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Allergic Reactions02:06

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
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Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
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Acute allergic rhinitis.

Robin J Green1, Andre Van Niekerk, Marinda McDonald

  • 1Department of Paediatrics and Child Health, University of Pretoria, Pretoria. robin.green@up.ac.za.

South African Family Practice : Official Journal of the South African Academy of Family Practice/Primary Care
|October 15, 2020
PubMed
Summary
This summary is machine-generated.

Acute exacerbations of allergic rhinitis require a new management approach. Recognizing triggers and using relief therapies, like nasal decongestants, are key to managing allergic rhinitis effectively.

Keywords:
acute exacerbationsallergensallergic rhinitisintranasal steroidstopical decongestantstriggers

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Area of Science:

  • Allergy and Immunology
  • Otolaryngology

Background:

  • Allergic rhinitis is a prevalent condition with established basic management strategies.
  • Acute exacerbations of chronic allergic rhinitis are frequently observed but inadequately addressed.
  • Existing management approaches may not fully encompass the complexities of allergic rhinitis exacerbations.

Purpose of the Study:

  • To highlight the need for a revised therapeutic approach for managing acute exacerbations of allergic rhinitis.
  • To define key events necessitating a new management strategy for allergic rhinitis.
  • To emphasize the importance of trigger identification and targeted relief therapies.

Main Methods:

  • Review of clinical scenarios illustrating challenges in allergic rhinitis management.
  • Identification of critical points in the patient journey requiring specific interventions.
  • Discussion of therapeutic strategies for acute symptom relief.

Main Results:

  • Three distinct scenarios underscore the inadequacy of current management for allergic rhinitis exacerbations.
  • Recognition of environmental and other triggers is crucial for effective intervention.
  • Topical nasal decongestants are identified as important 'relief' therapies.

Conclusions:

  • A new therapeutic approach is necessary to manage acute exacerbations of allergic rhinitis.
  • Effective management hinges on identifying triggers and employing appropriate relief strategies.
  • Implementing an 'action plan,' similar to asthma management, can improve patient outcomes.