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Related Experiment Video

Updated: Dec 5, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Spiny keratoderma.

M Corral¹, C Paret, M Iglesias

¹Department of Dermatology, Hospital Universitari Sagrat Cor, Barcelona. marinacf1990@gmail.com.

Dermatology Online Journal

|October 15, 2020

Summary

This summary is machine-generated.

Spiny keratoderma, a rare skin condition with spiky lesions on hands and feet, can be acquired and linked to cancers. This case highlights its association with endometrial carcinoma, a type of uterine cancer.

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Area of Science:

Dermatology
Oncology

Background:

Spiny keratoderma is a rare skin condition presenting with filiform keratotic papules on the palms and soles.
While some cases are inherited, most are acquired and can be idiopathic or secondary to underlying conditions.
Acquired spiny keratoderma has been linked to neoplasms and chronic systemic diseases, indicating a potential paraneoplastic phenomenon.

Observation:

A new case of spiny keratoderma was observed.
The patient presented with characteristic filiform keratotic lesions.

Findings:

The acquired spiny keratoderma in this case was associated with endometrial carcinoma.
This finding suggests a potential link between the skin condition and gynecological malignancy.

Implications:

This case expands the known associations of spiny keratoderma.
Early detection of endometrial carcinoma may be aided by recognizing associated dermatological signs.