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Anti-LGI1 Encephalitis Developing Immunoglobulin Responsive Orthostatic Hypotension after Remission

Kenta Orimo1, Nobue K Iwata1, Mizuho Kawai1

  • 1Department of Neurology, International University of Health and Welfare Mita Hospital, Japan.

Internal Medicine (Tokyo, Japan)
|October 15, 2020
PubMed
Summary

Anti-leucine-rich glioma-inactivated 1 (LGI1) antibody encephalitis can cause severe orthostatic hypotension (OH). This case shows OH improved with immunoglobulin therapy, suggesting a link between anti-LGI1 antibodies and autonomic dysfunction.

Keywords:
autonomic dysfunctionleucine-rich glioma-inactivated 1 (LGI1)limbic encephalitisorthostatic hypotension (OH)tilt testvoltage-gated potassium channel (VGKC)

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