Physiological factors influencing salivary clearance of sugar and fluoride

The salivary clearance of sugar and fluoride is influenced by several physiological factors not yet fully investigated or understood. There are reasons to believe that these factors influence both the acid production by sugar fermentation in the dental plaque and the cariostatic action of fluoride on the enamel surface and its immediate environment. This paper presents theoretical and experimental considerations of physiological factors which influence the kinetics of sugar and fluoride in the oral cavity.