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Updated: Dec 5, 2025

In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility
Published on: April 21, 2022
[Visualization of retinal blood flow disturbances in acute retinal ischemia syndrome]
I V Zlobin1, S I Zhukova1, T N Yuryeva1,2
1Irkutsk Branch of S.N. Fyodorov National Medical Research Center «MNTK «Eye Microsurgery», Irkutsk, Russia.
Abstract:
Vascular disorders account for a significant proportion of acute loss of vision. In recent years, scientific and technical progress in ophthalmology has provided new opportunities in the study of vascular pathology, significantly expanding the understanding of their pathogenesis. The article presents a clinical case of a patient with acute retinal ischemia syndrome who had retinal blood flow disturbances studied using optical coherence tomography (OCT) imaging. It demonstrates extensive possibilities of diagnostics of ischemic retinal lesions using OCT angiography that make this method the most informative in terms of evaluating the blood flow at different levels, independently in each vascular plexus.

