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Updated: Dec 5, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Previously Undetected Obstructive Sleep Apnea in Patients With New-Onset Atrial Fibrillation.
Victor Bazan1, Ignacio Vicente2, Lourdes Lozano3
1Cardiology Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; CIBERCV, Ciber de Enfermedades Respiratorias, Madrid, Spain. Universitat Autonoma de Barcelona. Barcelona. Spain.
Obstructive sleep apnea (OSA) is common in new-onset atrial fibrillation (AF). A STOP-BANG score of 4 or higher effectively identifies patients needing continuous positive airway pressure (CPAP) therapy.
Area of Science:
- Cardiology
- Sleep Medicine
- Pulmonology
Background:
- Obstructive sleep apnea (OSA) significantly impacts atrial fibrillation (AF) management.
- Continuous positive airway pressure (CPAP) may improve AF control, particularly in early stages.
Purpose of the Study:
- To evaluate a practical screening strategy for identifying new-onset AF patients likely to benefit from CPAP.
- To determine the predictive value of questionnaires versus conventional risk factors for CPAP indication.
Main Methods:
- Prospective evaluation of 73 new-onset AF patients using Epworth, Berlin, and STOP-BANG questionnaires.
- Ambulatory polysomnography to determine apnea-hypopnea index (AHI).
- Descriptive, univariate, and multivariate analyses to identify predictors of OSA and CPAP need.
Main Results:
- OSA prevalence was 82%, with 37% requiring CPAP.
- Male gender, BMI, obesity, hypertension, and high scores on Berlin/STOP-BANG questionnaires correlated with higher AHI.
- STOP-BANG score (≥4) was the sole predictor of CPAP indication (OR 4.5, p=0.01), with 76% sensitivity and 65% specificity.
Conclusions:
- New-onset AF patients exhibit a high prevalence of OSA and a significant need for CPAP.
- A STOP-BANG score of ≥4 serves as a practical and effective screening tool for CPAP indication in this population, potentially reducing the need for immediate polysomnography.
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