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Updated: Dec 5, 2025

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
The Risk of Contracting COVID-19 Is Not Increased in Patients With Celiac Disease
Jamie Zhen1, Juan Pablo Stefanolo2, Maria de la Paz Temprano2
1Farncombe Family Digestive Health Research Institute, McMaster University Medical Center, Hamilton Health Sciences, Hamilton, Ontario, Canada.
Insights
Patients with celiac disease (CeD) may face a higher risk of contracting COVID-19. This study investigated the potential link between CeD and coronavirus disease-2019 risk.
Area of Science:
- Immunology
- Infectious Diseases
- Gastroenterology
Background:
- The World Health Organization declared coronavirus disease-2019 (COVID-19) a global pandemic in March 2020, resulting in millions of cases and deaths worldwide.
- Celiac disease (CeD) is an immune-mediated gastrointestinal disorder triggered by gluten ingestion.
- Existing research indicates a correlation between CeD and an elevated risk of respiratory infections, but its association with COVID-19 remains unexplored.
Purpose of the Study:
- To investigate whether individuals with self-reported celiac disease (CeD) have an increased risk of contracting COVID-19.
- To address the knowledge gap concerning the relationship between celiac disease and COVID-19 susceptibility.
Main Methods:
- A cross-sectional study design was employed.
- Data was collected to assess the prevalence of COVID-19 among patients with self-reported celiac disease.
Main Results:
- The study evaluated the association between self-reported celiac disease and the risk of contracting COVID-19.
- Findings will elucidate whether CeD is a risk factor for COVID-19 infection.
Conclusions:
- The study aims to determine if celiac disease increases the risk of COVID-19.
- Results will inform clinical understanding and patient guidance regarding COVID-19 risk in CeD populations.
Abstract:
The World Health Organization declared coronavirus disease-2019 (COVID-19) a global pandemic in March 2020. Since then, there are more than 34 million cases of COVID-19 leading to more than 1 million deaths worldwide. Numerous studies suggest that celiac disease (CeD), a chronic immune-mediated gastrointestinal condition triggered by gluten, is associated with an increased risk of respiratory infections.1-3 However, how it relates to the risk of COVID-19 is unknown. To address this gap, we conducted a cross-sectional study to evaluate whether patients with self-reported CeD are at an increased risk of contracting COVID-19.
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