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Concussion Alters Dynamic Pupillary Light Responses in Children
Jerry Hsu1,2,3, Magdalena Stec2,3, Hantamalala Ralay Ranaivo2
1Department of Ophthalmology, 12244Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Journal of Child Neurology
|October 16, 2020
Summary
Pediatric concussion alters dynamic pupillary responses, with faster constriction and dilation velocities observed. Pupillometry offers insights into concussion-related physiological changes in children.
Area of Science:
- Ophthalmology
- Neurology
- Pediatrics
Background:
- Concussion, a common brain injury in children, can lead to visual disturbances.
- Pupillary function is a sensitive indicator of neurological status.
Purpose of the Study:
- To investigate the impact of concussion on pupillary function in children.
- To assess differences in pupillometric parameters between children with and without photosensitivity post-concussion.
Main Methods:
- Retrospective chart review of 92 pediatric patients with concussion and visual symptoms.
- Pupillometry data analyzed and compared to normative pediatric data.
- Linear mixed models used to assess the association between photosensitivity and pupillary responses.
Main Results:
- Concussion patients exhibited significantly faster average constriction velocity, maximum constriction velocity, and average dilation velocity compared to controls.
- A significant increase in 75% recovery time was observed in concussion patients.
- Photosensitivity did not significantly influence the measured pupillary responses.
Conclusions:
- Dynamic pupillary responses, including constriction and dilation velocities, appear altered in pediatric concussion.
- Pupillometry may serve as a valuable tool for understanding the pathophysiological changes associated with pediatric concussion.
