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Computational optical imaging with a photonic lantern
Debaditya Choudhury1,2, Duncan K McNicholl1,2, Audrey Repetti3,4
1Institute of Photonics and Quantum Sciences, Heriot-Watt University, Edinburgh, EH14 4AS, UK.
Nature Communications
|October 16, 2020
Summary
High-resolution in-vivo imaging is achieved using a multicore fiber (MCF) and a photonic lantern. This novel approach enables single-pixel imaging for enhanced biological process visualization.
Area of Science:
- Biomedical Optics
- Optical Engineering
- Computational Imaging
Background:
- Optical fibers are ideal for in-vivo biological imaging due to their flexibility.
- Current microendoscopic techniques face limitations in achieving high spatial resolution.
- Need for advanced imaging modalities to overcome resolution barriers in biological studies.
Purpose of the Study:
- To develop a high-resolution microendoscopy technique using multicore fibers (MCF).
- To demonstrate a novel single-pixel imaging approach for in-vivo biological visualization.
- To introduce a computational imaging algorithm for reconstructing images from MCF-based data.
Main Methods:
- Utilized a multicore fiber (MCF) with a tapered photonic lantern transition at the distal end.
- Individually excited single-mode MCF cores to project distinct, stable multimode light patterns.
- Employed a single-pixel detector to measure transmitted light fractions for each pattern.
- Developed and applied the SARA-COIL computational imaging algorithm for image reconstruction.
Main Results:
- Demonstrated stable projection of distinct multimode light patterns from the photonic lantern.
- Successfully implemented single-pixel imaging by measuring transmitted light through an object.
- Reconstructed object images using the SARA-COIL algorithm and pre-measured light patterns.
- Achieved high-resolution microendoscopy, overcoming limitations of current methods.
Conclusions:
- The developed MCF-based photonic lantern system offers a route to high-resolution microendoscopy.
- Single-pixel imaging combined with computational reconstruction provides a viable method for in-vivo biological imaging.
- This technology has the potential to significantly advance the visualization of biological processes.
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