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Hypoplastic left heart syndrome [HLHS]: treatment options in present era

Vivek Rai1, Marcin Gładki1, Mirosława Dudyńska1

  • 1Department of Pediatric Cardiac Surgery, Jagiellonian University Children's Hospital, Ul. Wielicka 265, 30-663 Krakow, Poland.

Indian Journal of Thoracic and Cardiovascular Surgery
|October 16, 2020
PubMed

Insights

Hypoplastic left heart syndrome (HLHS) treatment has advanced significantly with innovative diagnostics and surgical techniques. Staged palliative procedures, including hybrid interventions, improve survival and quality of life for HLHS patients.

Area of Science:

  • Pediatric Cardiology
  • Congenital Heart Disease Research
  • Surgical Innovation

Background:

  • Hypoplastic left heart syndrome (HLHS) is a severe congenital heart defect (CHD).
  • The Norwood procedure in 1983 marked the first successful intervention.
  • Treatment has evolved through pre-, intra-, and postoperative advancements.

Purpose of the Study:

  • To outline optimal strategies for improving survival and quality of life in HLHS patients.
  • To highlight advancements in diagnostic and surgical interventions.
  • To discuss the evolving role of interventional cardiology in HLHS management.

Main Methods:

  • Review of pre-, intra-, and postoperative treatment options.
  • Analysis of early diagnostic management and prenatal interventions.
  • Evaluation of modified surgical techniques and hybrid approaches.

Main Results:

  • Significant progress in HLHS treatment options due to early diagnosis, prenatal interventions, and innovative methods.
  • Hybrid and interventional cardiology enable stepwise treatment, potentially reducing the need for multiple surgeries.
  • The first stage of treatment can be safely performed directly or as a bridge to the Norwood procedure.

Conclusions:

  • Optimized strategies are crucial for enhancing HLHS patient outcomes.
  • Hybrid procedures and interventional cardiology offer promising alternatives for staged palliation.
  • Continued innovation in surgical techniques and diagnostics is vital for advancing HLHS care.

Keywords:
Congenital heart defectHypoplastic left heart syndromeSingle ventricle

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