Related Experiment Video
Updated: Dec 5, 2025

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
Published on: January 29, 2018
Bone loss, low height, and low weight in different populations and district: a meta-analysis between vegans and
Jianfeng Li1, Ruiyun Zhou2, Wei Huang1
1Department of Spine and Osteology, Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University), Zhuhai, Guangdong Province, China.
Objective:
The aim of this study was to- conduct a meta-analysis of the association of bone mineral density, height, and weight in different populations between vegans and non-vegans.
Methods:
Based on a search of PubMed, Web of Science, MEDLINE, the Cochrane Library, the Wanfang database, and the CNKI database, 14 relevant publications were collected by two researchers. Review Manager 5.3 and Stata 12.0 software were used for data analysis.
Results:
The following results were observed in this study: 1) the density of lumbar vertebrae was higher in vegans than in non-vegans (mean difference: -0.05, 95% CI: -0.09 to -0.01, P = 0.01); 2) hip bone density was higher in non-vegans than in vegans (mean difference: -0.08, 95% CI: -0.14 to -0.02, P = 0.008); 3) weight was higher in non-vegans than in vegans (mean difference: -2.21, 95% CI: -4.05 to -0.37, P = 0.02); and 4) height was higher in non-vegans than in vegans (mean difference: -1.87, 95% CI: -2.52 to -1.22, P < 0.00001).
Conclusion:
Our study suggests that a vegetarian lifestyle may contribute to bone loss, low height, and low weight based on existing evidence.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Study Designs in Epidemiology
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Hormones and Bone Tissue
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Bone Remodeling
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...

