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Hiccups: You got to be kidney me!
Viva Nguyen1, Khaled Deeb1, Ranga Rathakrishnan2
1Internal Medicine Resident, University of Miami JFK GME, Atlantis, FL, USA.
SAGE Open Medical Case Reports
|October 16, 2020
Summary
Persistent hiccups can signal serious kidney problems. This case highlights how acute kidney injury, identified by oxalate crystals, can cause intractable hiccups, resolving with dialysis.
Area of Science:
- Nephrology
- Internal Medicine
- Gastroenterology
Background:
- Persistent hiccups (intractable hiccups) lasting over 48 hours warrant comprehensive investigation.
- Toxic-metabolic derangements, such as renal dysfunction and uremia, are recognized causes of hiccups.
Observation:
- A 62-year-old male presented with persistent hiccups and rapidly declining renal function.
- Initial workup for intrinsic renal disease yielded negative results.
Findings:
- Kidney biopsy revealed acute tubular injury with oxalate crystals and interstitial fibrosis.
- Initiation of dialysis led to the resolution of hiccups.
- Kidney function gradually improved following dialysis treatment.
Implications:
- This case underscores the importance of considering renal dysfunction in patients with persistent hiccups.
- Acute kidney injury secondary to oxalate crystal deposition is a potential cause of intractable hiccups.
- Prompt diagnosis and management, including dialysis, can resolve hiccups and improve renal outcomes.
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