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Updated: Dec 5, 2025

Urethroplasty with Pedicled Tunica Vaginalis for the Treatment of Long-segment Anterior Urethral Stricture Caused by Lichen Sclerosus of Glans Penis
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Urethroplasty with Pedicled Tunica Vaginalis for the Treatment of Long-segment Anterior Urethral Stricture Caused by Lichen Sclerosus of Glans Penis

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Anogenital lichen sclerosus.

Manjyot Manish Gautam1, Vasundhara Singh1, Nitin J Nadkarni1

  • 1Department of Dermatology, Dr. DY Patil Hospital and Research Centre, Navi Mumbai, Maharashtra, India.

Indian Journal of Sexually Transmitted Diseases and AIDS
|October 16, 2020
PubMed
Summary

Lichen sclerosus (LS) is a chronic inflammatory condition affecting the anogenital region. Early detection and management involving physical examination and treatments like corticosteroids are vital for this relapsing disease.

Keywords:
Balanitis xeroticakraurosis vulvaelichen sclerosus

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Area of Science:

  • Dermatology
  • Pathology

Background:

  • Lichen sclerosus (LS) is a chronic inflammatory condition.
  • It primarily affects the anogenital region and has a relapsing course.
  • LS can lead to destruction, functional impairment, atrophy, and malignant changes.

Purpose of the Study:

  • To provide a comprehensive overview of Lichen sclerosus.
  • To highlight the diagnostic and management challenges.
  • To emphasize the importance of early intervention and long-term follow-up.

Main Methods:

  • Review of historical descriptions and clinical presentations of LS.
  • Discussion of etiological factors including genetics, autoimmunity, infections, and trauma.
  • Emphasis on physical examination for disease assessment and management planning.

Main Results:

  • LS affects both sexes, with a 5:1 female preponderance.
  • Disease prevalence is difficult to ascertain due to asymptomatic initial phases.
  • Management options include corticosteroids, calcineurin inhibitors, retinoids, phototherapy, and surgery.

Conclusions:

  • Accurate physical examination is crucial for managing LS.
  • Self-examination and consistent long-term follow-up are necessary for patients.
  • A multidisciplinary approach may be required given the potential complications and varied patient pathways.