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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
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Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
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Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
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Related Experiment Video

Updated: Dec 5, 2025

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model
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Radiodermatitis in Patients With Cancer: Systematic Review and Meta-Analysis.

Pamela K Ginex1, Chelsea Backler1, Elizabeth Croson2

  • 1Oncology Nursing Society.

Oncology Nursing Forum
|October 16, 2020
PubMed
Summary

Effective management of radiodermatitis in cancer patients involves topical steroids and dressings. These interventions minimize skin damage and alleviate symptoms like pain and itching.

Keywords:
guidelinemeta-analysisradiation therapyradiodermatitissystematic review

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Area of Science:

  • Oncology
  • Dermatology
  • Evidence-Based Medicine

Background:

  • Radiodermatitis is a common side effect of radiation therapy in cancer patients.
  • Effective management strategies are crucial for improving patient quality of life during treatment.

Purpose of the Study:

  • To conduct a systematic review and meta-analysis on radiodermatitis management.
  • To inform the development of clinical guidelines for cancer patients.

Main Methods:

  • Updated systematic literature search through September 30, 2019.
  • Risk of bias assessed using Cochrane Collaboration tool.
  • Certainty of evidence evaluated using GRADE approach.

Main Results:

  • Topical steroids and dressings effectively minimize radiodermatitis and moist desquamation.
  • These interventions also reduce patient-reported pain and pruritus.
  • Other interventions like aloe vera, emu oil, oral curcumin, and topical calendula showed limited or no benefit, or increased risk.

Conclusions:

  • Topical steroids and dressings are recommended for managing radiodermatitis in cancer patients.
  • These strategies help mitigate skin damage and improve symptom relief.
  • Further research may refine optimal management protocols.