Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Burn Injuries01:22

Burn Injuries

3.7K
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
3.7K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

3.6K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
3.6K
Exercise and Cardiac Output01:17

Exercise and Cardiac Output

1.7K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
1.7K
Exercise and Muscle Performance01:27

Exercise and Muscle Performance

2.1K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
2.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acute effects of passive heat exposure on vascular function and exercise capacity in patients with chronic kidney disease.

American journal of physiology. Heart and circulatory physiology·2026
Same author

Response to the opinion paper by Bouchama (2025), entitled 'Redefining human heat limits: integrating molecular and evolutionary physiology'.

The Journal of physiology·2026
Same author

Reply to Bassett and Armstrong.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same author

Impact of Burn Injury Size on Critical Environmental Limits during Exercise in the Heat in Young and Middle-Aged Adults.

Medicine and science in sports and exercise·2026
Same author

Low-energy cooling strategies modulate biomarkers of kidney injury risk in older adults exposed to very hot and dry heat.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same author

Endothelial sensitivity to exercise-induced shear rate in older adults: effect of biological sex and acute folic acid consumption.

American journal of physiology. Heart and circulatory physiology·2026

Related Experiment Video

Updated: Dec 5, 2025

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice
10:00

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice

Published on: March 15, 2019

8.7K

Exercise Training Improves Microvascular Function in Burn Injury Survivors.

Steven A Romero, Gilbert Moralez1, Manall F Jaffery1

  • 1University of Texas Southwestern Medical Center and Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, TX.

Medicine and Science in Sports and Exercise
|October 16, 2020
PubMed
Summary

A 6-month exercise program improved microvascular function in burn survivors, suggesting vascular remodeling may play a role. This intervention offers a potential therapeutic approach for burn-related vascular maladaptations.

More Related Videos

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
02:49

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes

Published on: February 23, 2024

1.7K
Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach
09:01

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach

Published on: June 5, 2010

14.5K

Related Experiment Videos

Last Updated: Dec 5, 2025

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice
10:00

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice

Published on: March 15, 2019

8.7K
Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
02:49

Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes

Published on: February 23, 2024

1.7K
Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach
09:01

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach

Published on: June 5, 2010

14.5K

Area of Science:

  • Cardiovascular Physiology
  • Exercise Science
  • Burn Rehabilitation

Background:

  • Impaired vasodilator function is a common issue in individuals with well-healed burn injuries.
  • Current therapeutic interventions to address this vascular maladaptation are limited.
  • Understanding microvascular and macrovascular changes post-burn is crucial for effective rehabilitation.

Purpose of the Study:

  • To determine if a 6-month community-based exercise training program enhances microvascular dilator function in individuals with well-healed burn injuries.
  • To investigate if the magnitude of the burn injury affects the response to exercise training.
  • To assess the impact of exercise training on macrovascular dilator function.

Main Methods:

  • Assessed microvascular function (forearm reactive hyperemia) and macrovascular function (brachial artery flow-mediated dilation) before and after training.
  • Measured maximal vasodilatory response post-ischemic handgrip exercise as an indicator of microvascular remodeling.
  • Included nonburned control subjects and individuals with moderate and high body surface area burn injuries.

Main Results:

  • Community-based exercise training significantly increased microvascular dilator function in both control and burn injury groups.
  • The improvements in microvascular function were comparable across all groups, irrespective of burn severity.
  • No significant changes were observed in macrovascular dilator function post-training.

Conclusions:

  • A community-based exercise program effectively improves microvascular function in individuals with well-healed burn injuries.
  • Vascular remodeling may contribute to the observed improvements in microvascular function.
  • Exercise training presents a promising non-pharmacological intervention for burn survivors with impaired vasodilator function.