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Updated: Dec 5, 2025

Morphological and Functional Assessment of the Right Ventricle Using 3D Echocardiography
Published on: October 28, 2020
The right ventricle in "Left-sided" cardiomyopathies: The dark side of the moon
Luna Cavigli1, Marta Focardi1, Matteo Cameli1
1Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Viale M. Bracci, 16, 53100 Siena, Italy.
Insights
The right ventricle (RV), once overlooked, is crucial in diagnosing and predicting outcomes for left-sided cardiomyopathies. Advanced imaging now reveals its vital role in heart health and patient prognosis.
Area of Science:
- Cardiology
- Cardiac Imaging
- Cardiomyopathy Research
Background:
- The right ventricle (RV) has historically been neglected compared to the left ventricle (LV).
- Advances in non-invasive imaging, including myocardial deformation and cardiovascular magnetic resonance (CMR), have improved understanding of RV anatomy and function.
- The RV's role in cardiovascular disease, particularly its interdependence with the LV, is increasingly recognized.
Purpose of the Study:
- To review the diagnostic and prognostic value of the right heart in left-sided cardiomyopathies.
- To highlight the importance of assessing RV size and function using multimodality imaging.
- To emphasize the RV's contribution to understanding disease progression and patient outcomes.
Main Methods:
- Review of current evidence on right heart assessment in left-sided cardiomyopathies.
- Focus on multimodality imaging techniques (e.g., CMR, deformation imaging).
- Analysis of diagnostic and prognostic implications of RV size and function.
Main Results:
- RV dysfunction significantly impacts functional performance and outcomes in cardiomyopathies.
- RV assessment provides critical information for diagnosis and prognosis in left-sided heart conditions.
- Interdependence between RV and LV is a key factor in overall cardiac health.
Conclusions:
- The right ventricle is essential for comprehensive cardiac evaluation, especially in cardiomyopathies.
- Multimodality imaging of the RV is vital for accurate diagnosis and prognosis.
- Understanding RV function is key to managing patients with left-sided cardiomyopathies.
Abstract:
The right ventricle (RV) has long been regarded as the forgotten and neglected cardiac chamber and it has been overshadowed by the left ventricle (LV). However, in the last decades, important advances in non-invasive cardiac imaging, from myocardial deformation imaging to cardiovascular magnetic resonance (CMR), have overcome the challenges imposed by the complex anatomy of the right heart, leading to a deep understanding of cardiovascular physiology and pathophysiology. The importance of the RV in different cardiac disease is now unquestionable and the current evidence emphasizes the forgotten interdependent relationship between the right and the left heart and the pivotal role of RV dysfunction in determining functional performance and outcomes in many cardiac disorders and particularly in cardiomyopathies. The purpose of this review is to summarize the current evidence about the diagnostic and prognostic value of the right heart in the "left-sided" cardiomyopathies, highlighting the relevance to assess RV size and function by multimodality imaging techniques in order to obtain useful information for a proper diagnostic workup and for the prognosis.
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