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Area of Science:

  • Pharmacology
  • Palliative Care Medicine
  • Clinical Pharmacy

Background:

  • Individual medication response is influenced by numerous factors including genetics, comorbidities, and co-administered drugs.
  • Patients in palliative care face heightened risks of adverse drug reactions (ADRs) even at therapeutic doses.
  • ADRs can negatively impact quality of life and the dying process in palliative care settings.

Purpose of the Study:

  • To highlight the importance of understanding haloperidol's indications, benefits, and risks.
  • To emphasize the significance of haloperidol use in palliative care.
  • To inform healthcare professionals about potential adverse events associated with haloperidol in this patient population.

Main Methods:

  • Review of existing literature on medication response variability.
  • Analysis of haloperidol's pharmacological profile and clinical use in palliative care.
  • Discussion of risk factors contributing to ADRs in palliative care patients.

Main Results:

  • Haloperidol is a frequently used antipsychotic in palliative care.
  • The drug is recommended for palliative care emergency kits.
  • Comprehensive knowledge of haloperidol is crucial for safe and effective patient management.

Conclusions:

  • Palliative care patients are susceptible to adverse drug reactions due to multiple influencing factors.
  • Haloperidol, a common medication in palliative care, requires careful consideration of its benefits and risks.
  • Ensuring familiarity with haloperidol's profile is essential for optimizing care and minimizing harm in palliative settings.