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Updated: Dec 5, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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A brief overview on recent advances in spiro[chromane-2,4'-piperidine]-4(3H)-one-functionalized compounds in

Nitin G Ghatpande1, Jagannath S Jadhav2, Rajshekhar V Kaproormath3

  • 1Department of Pharmaceutical Chemistry, School of Health Science, University of KwaZulu-Natal, Durban 4041, South Africa; Unique Med Chem Laboratories, L-64, Chincholli MIDC, Solapur 413255, M.S., India.

Bioorganic & Medicinal Chemistry
|October 17, 2020
PubMed

Keywords:
4′-piperidine]-4(3H)-oneBiological activityPharmacophoresSpiro[chromane-2structure activity relationship (SAR)

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