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[SARS-COV-2 myocarditis. An update]
D Fard1, R Huguet1, A Koutsoukis1
1Inserm U955, Institut Mondor de recherche biomédicale, université Paris-Est Créteil, 94010 Créteil, France; Service de cardiologie, hôpital universitaire Henri-Mondor, AP-HP, 94010 Créteil, France.
Annales De Cardiologie Et D'Angeiologie
|October 18, 2020
Summary
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause cardiac injury, including acute myocarditis. This review explores the pathophysiology, diagnosis, and treatment of SARS-CoV-2-associated myocarditis.
Area of Science:
- Infectious Diseases
- Cardiology
- Pathophysiology
Background:
- The SARS-CoV-2 virus causes COVID-19, a disease with diverse manifestations.
- Initial reports focused on respiratory symptoms, but multi-organ damage is now recognized.
- Cardiac injury, particularly acute myocarditis, is a significant complication.
Purpose of the Study:
- To elucidate the pathophysiological basis of SARS-CoV-2 myocarditis.
- To review current literature on diagnosing and treating this cardiac condition.
Main Methods:
- Literature review and analysis of existing publications.
- Discussion of pathophysiological mechanisms.
- Synthesis of diagnostic and therapeutic strategies.
Main Results:
- SARS-CoV-2 infection can lead to direct viral myocardial damage or immune-mediated injury.
- Clinical presentation varies, requiring careful diagnostic evaluation.
- Treatment strategies are evolving, focusing on supportive care and managing inflammation.
Conclusions:
- SARS-CoV-2 myocarditis is a recognized clinical entity with complex pathophysiology.
- Early diagnosis and appropriate management are crucial for patient outcomes.
- Further research is needed to fully understand and treat this condition.
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