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Updated: Dec 5, 2025

Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
Radial Artery vs Bilateral Mammary Composite Y Coronary Artery Grafting: 15-Year Outcomes
Alistair G Royse1, Rinaldo Bellomo2, Colin F Royse3
1Department of Surgery, University of Melbourne, Parkville, Victoria, Australia; Department of Cardiothoracic Surgery, Royal Melbourne Hospital, Melbourne, Victoria, Australia; Department of Health Sciences, Swinburne University, Melbourne, Victoria, Australia.
Insights
Total arterial revascularization using radial artery (RAY) or bilateral internal mammary artery (BIMAY) grafts showed similar long-term survival. This study found no significant difference in survival rates between RAY and BIMAY bypass grafting for three-coronary territory disease.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Vascular Surgery
Background:
- Total arterial revascularization (TAR) for three-coronary territory disease can utilize Y-grafts with either radial artery (RAY) or bilateral internal mammary artery (BIMAY) conduits.
- Previous studies have not definitively compared the long-term outcomes of RAY versus BIMAY in TAR.
Purpose of the Study:
- To compare the long-term survival outcomes of RAY versus BIMAY in patients undergoing total arterial revascularization for three-coronary territory disease.
Main Methods:
- Retrospective analysis of two cardiac surgical databases (Sydney and Melbourne, Australia).
- Propensity score matching was used to compare 299 pairs of patients aged 66 years or younger, with no significant preoperative or operative differences.
- Survival data were collected from the national death registry and analyzed using the Kaplan-Meier method.
Main Results:
- Older age at surgery was the strongest predictor of mortality (HR 2.06, P < .001).
- No significant difference in all-cause mortality was observed between the RAY and BIMAY groups at 15 years (74.9% vs 76.2%, P = .211).
- Graft numbers were similar between groups (RAY: 4.0 ± 0.9, BIMAY: 3.9 ± 0.9).
Conclusions:
- Radial artery (RAY) and bilateral internal mammary artery (BIMAY) grafts provide similar long-term survival for total arterial revascularization in three-coronary territory disease.
- The choice between RAY and BIMAY may not significantly impact long-term survival in carefully selected patients.
Background:
Total arterial coronary revascularization for three coronary territory disease can be achieved with a second arterial conduit joined to the left internal mammary artery as a Y graft, by using either a radial artery (RAY) or a second mammary artery (BIMAY).
Methods:
Patients undergoing total arterial revascularization for three coronary territory disease were identified from two cardiac surgical databases (in Sydney and Melbourne, Australia) using Society of Thoracic Surgeons-based definitions. BIMAY-treated patients underwent surgery between 1994 and 2009, mostly using an age-limited protocol, whereas RAY-treated patients underwent surgery between 1996 and 2003 without age limits. All-cause mortality data were acquired from the national death registry, and survival was estimated by the Kaplan-Meier method. Propensity score matching was performed using 13 variables. Given the age imbalance between the groups, the primary comparison was performed for age 66 years or younger.
Results:
Overall, 1896 patients underwent RAY procedures, and 720 patients underwent BIMAY operations. Older age at surgery was the strongest independent predictor of mortality, with a hazard ratio of 2.06, and a 95% confidence interval of 1.93, 2.22 (P < .001). After propensity score matching, we identified 299 pairs of patients 66 years of age or younger with no preoperative or operative differences and similar ages at surgery: RAY 56.4 ± 7.0 years of age vs BIMAY 56.4 ± 6.8 years of age (P = .96). The RAY group had 4.0 ± 0.9 grafts, and the BIMAY group had 3.9 ± 0.9 grafts (P = .814). All-cause mortality was not different, with the proportion surviving at 15 years at 74.9% for the RAY group vs 76.2% for the BIMAY group (P = .211).
Conclusions:
Survival was not different between the RAY and BIMAY groups for total arterial revascularization of three coronary territory bypass grafting.
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