A Bird's eye view from below: Activity in the temporo-parietal junction predicts from-above Necker Cube percepts

The temporo-parietal junction (TPJ) consistently emerges in other-regarding behavior, including tasks probing affective phenomena such as morality and empathy. Yet the TPJ is also recruited in processes with no affective or social component, such as visuo-spatial processing and mathematical cognition. We present serendipitous findings from a perceptual decision-making task on a bistable stimulus, the Necker Cube, performed in an MRI scanner. The stimulus in question is a transparent, wire-frame cube that evokes spontaneous switches in perception. Individuals can view the cube from below or from above, though a consistent bias is shown towards seeing the cube from above. We replicate this bias, finding participants spend more time in the from-above percept. However, in testing for BOLD differences between percept orientations, we found robust responses in bilateral TPJ for the from-above > from-below perceptual state. We speculate that this neural response comes from the sensory incongruence of viewing an object from above while lying supine in the scanner. We further speculate that the TPJ resolves this incongruence by facilitating an egocentric projection. Such a function would explain the TPJ's ubiquitous response to other-regarding, visuo-spatial and mathematical cognition, as all these phenomena demand an ability to ambulate through the coordinate space. Our findings suggest the TPJ may not play a specific role in social or moral components of other-regarding behavior, such as altruism, and further indirectly suggest that "pure", allocentric altruism may not correlate with the TPJ. Results further have implications on how the TPJ may be modulated by activities such as flight or drone operation. Finally, this study highlights the possible need for congruence between stimuli and body position in neuroimaging studies.