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Relationship between cardio-ankle vascular index and obstructive sleep apnea
Yasuhiro Tomita1,2,3, Takatoshi Kasai2,3,4
1Cardiovascular Center, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, Japan.
Reviews in Cardiovascular Medicine
|October 19, 2020
Summary
Obstructive sleep apnea (OSA) patients face increased atherosclerosis and cardiovascular risks. The cardio-ankle vascular index (CAVI) effectively measures arterial stiffness and atherosclerosis, potentially improving risk prediction.
Area of Science:
- Cardiology
- Sleep Medicine
- Vascular Biology
Background:
- Obstructive sleep apnea (OSA) is linked to atherosclerosis and cardiovascular disease (CVD) risk.
- Arterial stiffness, a predictor of atherosclerosis, is a growing concern in OSA management.
- The cardio-ankle vascular index (CAVI) is a promising, blood-pressure-independent measure of arterial stiffness.
Purpose of the Study:
- To review the relationship between OSA and arterial stiffness, focusing on CAVI.
- To explore CAVI's utility in predicting atherosclerosis in OSA patients.
- To discuss the impact of OSA treatment on CAVI and propose future research directions.
Main Methods:
- Literature review of studies investigating OSA, atherosclerosis, and CAVI.
- Analysis of physiological parameters and their correlation with arterial stiffness.
- Evaluation of noninvasive measurement techniques for CAVI.
Main Results:
- Patients with OSA exhibit increased arterial stiffness, as indicated by higher CAVI.
- CAVI effectively predicts the degree of atherosclerosis independent of blood pressure.
- Continuous positive airway pressure (CPAP) therapy for OSA has been shown to reduce CAVI.
Conclusions:
- CAVI is a valuable tool for assessing arterial stiffness and atherosclerosis risk in OSA patients.
- Understanding the OSA-CAVI relationship can guide CVD prevention strategies.
- Further research on CAVI in OSA is warranted to optimize patient outcomes.
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