Increased burden of cardiovascular risk among youth suicide attempters
Yongqi Zhong1,2, Steven Pham3, Giovanna Porta4
1Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Insights
Young adults who attempt suicide have a higher cardiovascular risk burden than other high-risk groups. This highlights the need for clinicians to monitor cardiovascular health in suicide attempters to prevent adverse events.
Area of Science:
- Cardiology
- Psychiatry
- Public Health
Background:
- Suicide and cardiovascular disease are leading causes of premature mortality globally.
- Young adult suicide attempters exhibit higher cardiovascular disease mortality risk than those with major depressive disorder.
- This suggests a greater burden of cardiovascular risk factors among young suicide attempters.
Purpose of the Study:
- To compare the cardiovascular risk burden in youth suicide attempters versus other high-risk individuals.
- To identify specific cardiovascular risk factors in young adults with a history of suicide attempts.
Main Methods:
- Utilized data from the Collaborative Psychiatric Epidemiology Surveys (CPES) and an inpatient psychiatric sample.
- Included participants aged 15-30 years with varying histories of suicide attempt (SA), suicidal ideation (SI), or no psychiatric history.
- Calculated cardiovascular risk scores and classified individuals into high- and low-risk groups based on blood pressure, obesity, and smoking.
Main Results:
- Suicide attempters demonstrated significantly higher cardiovascular risk scores compared to controls in both population-based and inpatient samples.
- Youth suicide attempters were more likely to be in the high cardiovascular risk category than individuals with only suicidal ideation.
- The increased risk was evident across different sample types, indicating a consistent pattern.
Conclusions:
- Youth suicide attempters face a disproportionately high cardiovascular risk burden compared to other high-risk groups.
- Clinicians must prioritize screening and management of cardiovascular risk factors in all suicide attempters.
- Addressing these risks is crucial for reducing premature mortality from cardiovascular events in this vulnerable population.
Background:
Suicide and cardiovascular disease rank among the leading causes of disability and premature mortality worldwide. Young adult suicide attempters are at increased risk of mortality from cardiovascular disease even compared to those with major depressive disorder suggesting an increased burden of cardiovascular risk factors. We compared the cardiovascular risk burden between youth attempters and other high-risk individuals.
Methods:
Participants were from the Collaborative Psychiatric Epidemiology Surveys (CPES), a U.S. population-based study, aged 18-30 years [suicide attempt (SA): n = 303; suicidal ideation (SI): n = 451; controls: n = 3671]; and psychiatric inpatients admitted for a SA (n = 38) or SI (n = 40) and healthy controls (n = 37) aged 15-30 years. We computed a cardiovascular risk score and high- and low-risk latent classes based on risk factors of high blood pressure, obesity, and smoking.
Results:
Suicide attempters showed an increased cardiovascular risk score (CPES: B = 0.43, 95% confidence interval (CI) 0.31-0.54, p < 0.001; inpatient sample: B = 1.61, 95% CI 0.53-2.68, p = 0.004) compared to controls. They were also more likely to be classified in the high cardiovascular risk group (CPES: odds ratio (OR) 3.36, 95% CI 1.67-6.78, p = 0.001; inpatient sample: OR 9.89, 95% CI 1.38-85.39, p = 0.03) compared to those with SI (CPES: OR 1.15, 95% CI 0.55-2.39, p = 0.71; inpatient sample: OR 1.91, 95% CI 0.25-15.00, p = 0.53).
Conclusions:
Youth attempters show an increased burden for cardiovascular risk compared to other high-risk individuals in inpatient and population-based samples. Clinicians should pay particular attention to cardiovascular risk factors among suicide attempters in order to reduce their risk for cardiovascular events.
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