A disposable and sensitive non-enzymatic glucose sensor based on 3D graphene/Cu₂O modified carbon paper electrode

Herein, a three-dimensional graphene wall (GWs) and nano-Cu₂O modified carbon fiber paper (CFP) electrode were used to develop a disposable and sensitive non-enzymatic glucose sensor. This sensing interface of GWs/Cu₂O consists of an interlaced CFP on which intercrossed graphene walls (GWs) were vertically tethered in situ by radio frequency plasma enhanced chemical vapor deposition (RF-PECVD), and Cu₂O nanoparticles (NPs) were evenly grew on the 3D GWs layer and skeleton through the complete thermal decomposition of copper acetate (Cu (CH₃COO)₂) at high temperature. The CFP/GWs/Cu₂O shows a large specific surface area and rich solution diffusion channels, which can expose more catalytic active sites without Nafion fixation film, thus greatly improving the electrocatalytic performance of this glucose sensor. The CFP/GWs/Cu₂O sensor shows excellent catalytic performance to glucose with a linear detection range of 0.5 μM-5166 μM, LOD of 0.21 μM, and response time <4 s. This kind of disposable and sensitive electrode can capable of controlling uniform growth and accurate quantification, and has great development potential in the field of medical detection and the commercialization of wearable sensors.