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Effect of body mass index on intrauterine insemination cycle success
Rachel M Whynott1, Karen M Summers1, Bradley J Van Voorhis1
1Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Iowa Carver College of Medicine, Iowa City, Iowa.
Objective:
To determine whether body mass index (BMI) affects intrauterine insemination treatment success.
Design:
Retrospective cohort study.
Setting:
Academic medical center.
Patient(S):
A total of 3,217 intrauterine insemination treatment cycles in 1,306 patients.
Intervention(S):
None.
Main Outcome Measure(S):
Primary outcome was live birth rate stratified by BMI. Secondary outcomes included rates of clinical pregnancy (defined as an intrauterine pregnancy with a heartbeat present on ultrasound), multiple gestation, biochemical pregnancy, missed abortion, ectopic, and spontaneous abortion.
Result(S):
Women with BMI 25 to 29.99 kg/m2 or ≥30 kg/m2 were equally likely to have a live birth as women of normal BMI. Women with BMI ≥30 kg/m2 did have a higher likelihood of biochemical pregnancy than women with normal BMI.
Conclusion(S):
A BMI between 25 and 29.99 kg/m2 or ≥30 kg/m2 does not appear to have a negative effect on live birth after intrauterine insemination. Obesity may be associated with a higher risk of biochemical pregnancy after intrauterine insemination.
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