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Updated: Dec 5, 2025

Quantification of Orofacial Phenotypes in Xenopus
Published on: November 6, 2014
OROFACIAL CLEFTS AND CARDIOVASCULAR RISK AND DISEASES: THE CAUSAL RELATIONSHIP AND ASSOCIATIONS
C E Nwaze1, O Adebayo2, A M Adeoye3,4
1College of Medicine, University of Ibadan, Ibadan.
Abstract:
There is a complex interplay between orofacial clefts (OFCs) or cleft of the lip and palate and cardiovascular risk factors and cardiac diseases. The presence of maternal cardiovascular risk factors serves as a potent predisposing factor to the development of OFCs during foetal development in addition to the fact that various congenital anomalies are associated with OFCs either in syndromic or non-syndrome relationship. This article narratively explores this complex interplay, which is not uncommon.
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