Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Extreme metabolic acidosis. Case report.

P Sjøgren, L W Andersen

    Acta Anaesthesiologica Scandinavica
    |August 1, 1987
    PubMed
    Summary

    This case study highlights extreme lactic acidosis in a patient with insulin-dependent diabetes mellitus (IDDM). Effective treatment involved low-dose insulin and sodium bicarbonate, resolving the metabolic crisis.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Reply to comment on update of in-hospital Utstein guidelines.

    Resuscitation·2020
    Same author

    Tapering off long-term opioid therapy in chronic non-cancer pain patients: A randomized clinical trial.

    European journal of pain (London, England)·2018
    Same author

    Development of health-related quality of life and symptoms in patients with advanced cancer in Greenland.

    European journal of cancer care·2018
    Same author

    Socioeconomic status and risk of intensive care unit admission with sepsis.

    Acta anaesthesiologica Scandinavica·2018
    Same author

    Dental status in nursing home residents with domiciliary dental care in Sweden.

    Community dental health·2017
    Same author

    Circulating fatty acids in relation to alcohol consumption: Cross-sectional results from a cohort of 60-year-old men and women.

    Clinical nutrition (Edinburgh, Scotland)·2017

    Area of Science:

    • Endocrinology
    • Critical Care Medicine
    • Gastroenterology

    Background:

    • Insulin-dependent diabetes mellitus (IDDM) requires careful management to prevent acute complications.
    • Lactose intolerance can complicate fluid and electrolyte management.
    • Metabolic acidosis, particularly lactic acidosis, is a life-threatening diabetic emergency.

    Observation:

    • A 42-year-old male with IDDM and lactose intolerance presented with severe lactic acidosis.
    • Arterial blood gas analysis revealed profound acidosis (pH 6.79) and hyperglycemia (38 mmol/L).
    • Hypothermia (30°C) and signs of poor tissue perfusion were noted.

    Findings:

    • Uncontrolled hyperglycemia, diarrhea-induced fluid imbalance, and impaired tissue perfusion were identified as potential causes.
    • Treatment with low-dose insulin and isotonic sodium bicarbonate infusion led to a satisfactory clinical outcome.
    • The case demonstrates successful management of a complex metabolic derangement.

    Implications:

    • Highlights the importance of recognizing and managing severe lactic acidosis in diabetic patients.
    • Underscores the need for individualized treatment strategies considering comorbidities like lactose intolerance.
    • Emphasizes the efficacy of combined insulin and bicarbonate therapy in critical metabolic acidosis.

    Related Experiment Videos