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Related Experiment Video

Updated: Dec 5, 2025

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management
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Biobanking for COVID-19 research.

Patrizia Rovere-Querini1,2, Cristina Tresoldi3, Caterina Conte4

  • 1School of Medicine, Vita-Salute San Raffaele University, Milan, Italy - rovere.patrizia@hsr.it.

Panminerva Medica
|October 19, 2020
PubMed

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Summary

A COVID-19 biobank was rapidly established to collect biospecimens for research. This infrastructure facilitates knowledge sharing on SARS-CoV-2, aiding in developing new strategies against the virus.

Area of Science:

  • * Infectious Disease Research
  • * Biobanking and Sample Management
  • * Genomic and Proteomic Studies

Background:

  • * Biobanks are critical for rapid knowledge acquisition during disease outbreaks.
  • * Timely sharing of scientific information enables evidence-based health strategies.
  • * Established research infrastructures are vital for pandemic response.

Purpose of the Study:

  • * To establish a COVID-19 biobank (COVID-BioB) for collecting high-quality, annotated human biospecimens.
  • * To investigate the pathogenic mechanisms of COVID-19.
  • * To identify potential therapeutic targets for COVID-19.

Main Methods:

  • * Established the COVID-BioB biobank (NCT04318366) for COVID-19 research.
  • * Collected and annotated human biospecimens from participants.

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  • * Reviewed characteristics of established COVID-19 biobanks.

    • Main Results:

    • * Collected 46,677 samples from 913 participants (63.3% male, median age 62.2 years).
    • * 66.9% of participants were hospitalized for COVID-19, with a median stay of 15 days.
    • * 13.3% of participants tested positive for SARS-CoV-2 after admission for other reasons.

    Conclusions:

    • * A robust research infrastructure enabled the swift creation of the COVID-19 biobank.
    • * The biobank supports expanded knowledge sharing on SARS-CoV-2.
    • * Flexibility and adaptability were key to the successful establishment of the biobank.