Percutaneous coronary intervention for bifurcation coronary lesions: the 15th consensus document from the European

Francesco Burzotta1, Jens Flensted Lassen, Thierry Lefèvre

  • 1Insitute of Cardiology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

Insights

The 15th European Bifurcation Club meeting refined consensus on coronary bifurcation lesions (CBL) and unprotected left main interventions. While provisional stenting remains versatile, complex cases may benefit from two-stent techniques and novel tools.

Area of Science:

  • Interventional Cardiology
  • Cardiovascular Research

Background:

  • The 15th European Bifurcation Club (EBC) meeting convened to address advancements in percutaneous coronary interventions (PCI) for coronary bifurcation lesions (CBL).
  • Consensus was sought on optimal strategies for complex cases, including unprotected left main (LM) stenting.

Purpose of the Study:

  • To summarize the key discussions and consensus points from the 15th EBC meeting regarding coronary bifurcation stenting.
  • To highlight evolving techniques, ongoing debates, and future directions in the management of CBL and LM PCI.

Main Methods:

  • The meeting involved expert discussions and review of current evidence on bifurcation stenting techniques.
  • Focus areas included provisional versus two-stent strategies, side branch management, and the role of novel technologies.

Main Results:

  • A provisional stenting approach with optional side branch intervention (e.g., T-stenting, TAP, culotte) is suitable for most CBL patients.
  • Complex lesions, especially in the LM, may require dedicated two-stent techniques, emphasizing operator familiarity and final kissing inflation.
  • Intracoronary imaging, simulation, drug-eluting balloons, and tailored antiplatelet therapy show promise for improving outcomes.

Conclusions:

  • Bifurcation PCI strategies continue to evolve, integrating bench testing, clinical trials, and new technologies.
  • Further research is necessary to optimize clinical outcomes for all patients with coronary bifurcation lesions.

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