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Updated: Dec 5, 2025

A General Method for Evaluating Incubation of Sucrose Craving in Rats
Published on: November 4, 2011
Choice between different concentrations of sucrose in an adjusting-magnitude schedule: Evidence for
1Division of Psychiatry, University of Nottingham, UK.
Abstract:
According to the Multiplicative Hyperbolic Model (MHM), an extension of Mazur's (1987) model of delay discounting, the value of a reinforcer is an increasing hyperbolic function of its size (q). This experiment tested a prediction based on a revised version of MHM (MHM-R), according to which the maximum value may differ between different reinforcers, a possibility not envisaged in MHM. Rats were trained under a discrete-trials adjusting-magnitude schedule in which a response on lever B delivered a dilute sucrose reinforcer (0.2 M) of fixed volume, qB, while a response on lever A delivered a more concentrated sucrose solution (0.4 M) the volume of which, qA, was adjusted according to the rats' choices. When B was preferred in a given block of trials, qA was increased in the following block; when A was preferred, qA was reduced in the following block. qB was varied across four phases of the experiment and the corresponding indifference magnitudes of A (qA(50)) were measured. In keeping with expectations based on both MHM and MHM-R, qA(50) increased approximately linearly with qB, and 1/qA(50) with 1/qB. The ratio qB/qA(50) increased linearly with qB with a positive intercept, a finding that is consistent with MHM-R but not with MHM.
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