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Updated: Dec 5, 2025

Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs
Published on: November 8, 2024
The 1H T1 dispersion curve of fentanyl citrate to identify NQR parameters
Michael W Malone1, Michelle A Espy1, Sun He2
1Los Alamos National Laboratory, Los Alamos, NM, USA.
Abstract:
We report the 1H T1 dispersion curve between 0 and 5 MHz for the synthetic opioid fentanyl citrate (C28H36N2O8). The structures in the curve can be used to estimate the 14N nuclear quadrupole resonance (NQR) frequencies of the material. Density functional theory predictions of the NQR parameters of several fentanyl citrate compounds are also reported. The predictions for the aniline nitrogen are consistent with structures in the observed T1 data. To help interpret the fentanyl citrate results the T1 dispersion curve for the explosive ammonium nitrate is also presented.
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