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Nasal pain as an aura: Amygdala origin?
Kyoung Heo1, Kyung Min Kim1, Seung Min Han1
1Department of Neurology, Epilepsy Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Seizure
|October 19, 2020
Summary
Nasal pain can be an unrecognized epileptic aura, often linked to temporal lobe epilepsy. This study highlights clinical features and probable amygdala involvement in patients experiencing nasal pain as an aura.
Area of Science:
- Neurology
- Epilepsy Research
- Neuroimaging
Background:
- Nasal pain as an epileptic aura is poorly recognized.
- Understanding aura characteristics is crucial for epilepsy diagnosis and management.
Purpose of the Study:
- To demonstrate the clinical features of patients with epilepsy experiencing nasal pain as an aura.
- To investigate the potential link between nasal pain aura and temporal lobe epilepsy.
Main Methods:
- Retrospective investigation of patients with epilepsy presenting with nasal pain aura.
- High-resolution magnetic resonance imaging (MRI) analysis of all included patients.
- Electroencephalogram (EEG) analysis to identify epileptiform discharges.
Main Results:
- Seven patients with nasal pain as an aura were identified.
- Four patients showed right amygdala enlargement, with EEG anomalies ipsilateral to the enlargement.
- Nasal pain was associated with other aura symptoms and focal impaired awareness seizures, typical of mesial temporal lobe epilepsy.
Conclusions:
- Nasal pain can manifest as an epileptic aura, particularly in temporal lobe epilepsy.
- The amygdala may be involved in the generation of nasal pain auras.
- Further research is warranted to fully elucidate the mechanisms of nasal pain as an epileptic aura.
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