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Related Concept Videos

Teratogenicity01:07

Teratogenicity

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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Symbiosis00:58

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Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
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Related Experiment Video

Updated: Dec 5, 2025

Toxoplasma gondii Cyst Wall Formation in Activated Bone Marrow-derived Macrophages and Bradyzoite Conditions
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Toxoplasmosis in pregnancy.

Maimoona Ahmed1, Akanksha Sood2, Janesh Gupta3

  • 1Women's Health Department, Aldara Hospital and Medical Centre, Riyadh, Saudi Arabia.

European Journal of Obstetrics, Gynecology, and Reproductive Biology
|October 19, 2020
PubMed
Summary

Toxoplasmosis infection during pregnancy poses a significant risk of congenital toxoplasmosis, potentially causing severe fetal harm. Early diagnosis and antibiotic treatment are crucial for reducing transmission and protecting the fetus.

Keywords:
Congenital toxoplasmosisMother-to-child transmissionToxoplasmosis

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Area of Science:

  • Medical Parasitology
  • Infectious Diseases
  • Maternal-Fetal Medicine

Background:

  • Toxoplasmosis, a chronic infection by *Toxoplasma gondii*, is common.
  • While often asymptomatic in non-pregnant women, it poses severe risks during pregnancy via vertical transmission.
  • Congenital toxoplasmosis can lead to irreversible neurological damage and blindness in newborns.

Purpose of the Study:

  • To highlight the risks of toxoplasmosis in pregnancy.
  • To emphasize the importance of screening and early intervention.
  • To underscore the role of primary prevention and patient education.

Main Methods:

  • Review of existing literature on toxoplasmosis epidemiology and outcomes.
  • Analysis of the impact of screening programs and antibiotic therapy.
  • Assessment of preventative strategies, including patient education.

Main Results:

  • *Toxoplasma gondii* infection during pregnancy can cause severe congenital defects.
  • Screening programs vary globally based on regional parasite prevalence and virulence.
  • Antibiotic therapy significantly reduces the risk of fetal transmission.

Conclusions:

  • Prompt diagnosis and antibiotic treatment are vital for managing toxoplasmosis in pregnant individuals.
  • Primary prevention through patient education is essential to avoid *Toxoplasma gondii* infection.
  • Effective management strategies are critical to mitigate the impact of congenital toxoplasmosis.