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Continuous singlet oxygen generation for persistent chemiluminescence in Cu-MOFs-based catalytic system
Chang Ping Yang1, Li He1, Cheng Zhi Huang2
1Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China.
New flower-like copper metal-organic frameworks (Cu-MOFs) catalyze the luminol-hydrogen peroxide system, producing persistent chemiluminescence (CL). This breakthrough enables sensitive detection of quercetin, offering a novel approach for CL catalyst development.
Area of Science:
- Materials Science
- Analytical Chemistry
- Catalysis
Background:
- Chemiluminescence (CL) from luminol-hydrogen peroxide systems is typically weak and short-lived.
- Developing efficient catalysts is essential to enhance CL intensity and duration for practical applications.
Purpose of the Study:
- To synthesize and characterize flower-like copper metal-organic frameworks (Cu-MOFs) derived from Cu-based metal-organic gels (Cu-MOGs).
- To investigate the catalytic performance of Cu-MOFs in the luminol-hydrogen peroxide system for persistent CL emission.
- To establish a sensitive detection method for quercetin based on the enhanced CL system.
Main Methods:
- Synthesis of Cu-MOFs with flower morphology from Cu-MOGs.
- Catalytic evaluation of Cu-MOFs in the luminol-H2O2 system.
- Mechanism study involving reactive oxygen species (ROS) generation and recombination.
- Development of a CL-based analytical method for quercetin detection.
Main Results:
- Cu-MOFs successfully catalyzed the luminol-H2O2 system, producing persistent CL emission.
- The persistent CL mechanism involves the gradual generation and recombination of hydroxyl radicals (OH˙), superoxide radicals (O2˙-), and singlet oxygen (1O2) on the Cu-MOF surface.
- A sensitive detection strategy for quercetin was developed, showing good linearity (0.05-1.2 μM) and a low detection limit (49.7 nM).
Conclusions:
- Flower-like Cu-MOFs are effective catalysts for generating persistent chemiluminescence in the luminol-H2O2 system.
- The prolonged CL emission is attributed to the sustained generation and recombination of ROS, particularly singlet oxygen.
- The developed Cu-MOF-based CL system offers a promising platform for sensitive and selective detection of analytes like quercetin.
