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Association between Obstructive Sleep Apnea and SYNTAX Score.
Sayaki Ishiwata1,2, Yasuhiro Tomita3,4, Sugao Ishiwata3
1Department of Cardiovascular Medicine, Juntendo University School of Medicine, Tokyo 113-8421, Japan.
Journal of Clinical Medicine
|October 20, 2020
Summary
Moderate-to-severe obstructive sleep apnea (OSA) is linked to more severe coronary artery disease (CAD). This finding highlights the importance of diagnosing and treating OSA in patients with heart conditions.
Area of Science:
- Cardiology
- Sleep Medicine
- Internal Medicine
Background:
- Obstructive sleep apnea (OSA) is associated with increased cardiovascular disease risk.
- Coronary artery disease (CAD) is a significant cardiovascular complication.
- The relationship between OSA severity and CAD severity requires further investigation.
Purpose of the Study:
- To investigate the association between the severity of obstructive sleep apnea (OSA) and the severity of coronary artery disease (CAD).
- To assess if OSA severity correlates with the extent of coronary artery blockages.
Main Methods:
- Retrospective analysis of 98 patients undergoing coronary angiography and polysomnography (PSG) between March 2002 and May 2015.
- CAD severity was quantified using the SYNTAX score.
- Patients were categorized into mild OSA (apnea-hypopnea index [AHI] < 15/h) and moderate-to-severe OSA (AHI ≥ 15/h) groups.
Main Results:
- A significant difference in SYNTAX scores was observed between the mild and moderate-to-severe OSA groups (p = 0.001).
- After adjusting for cardiovascular risk factors, moderate-to-severe OSA showed a significant positive correlation with the SYNTAX score (partial r = 0.24, p = 0.039).
Conclusions:
- The findings suggest a significant relationship between moderate-to-severe OSA and increased coronary artery disease severity.
- This indicates that OSA may be an independent risk factor contributing to the progression of CAD.
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