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Biomimetic two-dimensional nanozymes: synthesis, hybridization, functional tailoring, and biosensor applications
1College of Chemistry and Chemical Engineering, Qingdao University, 266071 Qingdao, P. R. China. weigroup@qdu.edu.cn.
Journal of Materials Chemistry. B
|October 20, 2020
Summary
Two-dimensional (2D) nanomaterials are emerging as promising nanozymes, overcoming limitations of biological enzymes. These 2D nanozymes offer enhanced stability and reusability for applications in biosensing and environmental remediation.
Area of Science:
- Materials Science
- Nanotechnology
- Biochemistry
Background:
- Biological enzymes are crucial catalysts but suffer from cost, stability, and reusability issues.
- Functional nanomaterials, termed nanozymes, are developed to mimic enzyme properties.
- Two-dimensional (2D) nanomaterials offer unique properties for advanced nanozyme applications.
Purpose of the Study:
- To review recent advancements in the preparation and functionalization of 2D material-based nanozymes.
- To explore the diverse applications of these nanozymes, particularly in biosensing and immunoassays.
- To highlight the potential of 2D nanozymes in overcoming natural enzyme limitations.
Main Methods:
- Summarizing various preparation strategies for 2D nanozymes, including chemical reduction, exfoliation, and hydrothermal synthesis.
- Discussing the structural and property modifications of 2D nanozymes through conjugation with other materials (nanoparticles, metal oxides, biomolecules, etc.).
- Reviewing the application of these nanozymes in different sensing platforms like colorimetric, electrochemical, and fluorescent sensors.
Main Results:
- Diverse 2D nanomaterials can be synthesized into effective nanozymes using multiple strategies.
- Conjugation of 2D materials with various components enhances nanozyme performance and expands their functionality.
- 2D nanozymes demonstrate significant potential in developing sensitive and specific biosensors and immunoassays.
Conclusions:
- 2D material-based nanozymes represent a significant advancement over traditional biological enzymes.
- Their unique properties and versatile preparation methods enable broad applications in diagnostics and environmental monitoring.
- Further research into 2D nanozymes promises innovative solutions in various scientific and technological fields.
