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Chikungunya Virus Infection in Blood Donors and Patients During Outbreak, Mandalay, Myanmar, 2019
Insights
A 2019 chikungunya virus outbreak in Myanmar infected 6.3% of blood donors and 20.5% of child patients. The East Central/South African genotype was the primary circulating strain during this public health event.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- Chikungunya virus (CHIKV) poses a significant public health threat globally.
- Understanding CHIKV outbreaks is crucial for effective disease control.
Purpose of the Study:
- To characterize the 2019 chikungunya virus outbreak in Mandalay, Myanmar.
- To determine the prevalence and circulating genotype of CHIKV during the outbreak.
Main Methods:
- Retrospective analysis of laboratory-confirmed chikungunya virus cases.
- Analysis of blood donor and pediatric patient data from Mandalay, Myanmar.
- Genotyping of circulating CHIKV strains.
Main Results:
- The 2019 outbreak in Mandalay, Myanmar, showed a CHIKV prevalence of 6.3% among blood donors.
- Infected individuals included 20.5% of pediatric patients.
- The East Central/South African genotype was identified as the predominant circulating strain.
Conclusions:
- The 2019 outbreak highlighted the significant burden of chikungunya virus infection in Mandalay.
- The predominance of the East Central/South African genotype has implications for disease surveillance and control strategies.
- Further research is needed to understand long-term CHIKV epidemiology in the region.
Abstract:
In 2019, an outbreak of chikungunya virus infection occurred in Mandalay, Myanmar, and 3.2% of blood donors and 20.5% of patients who were children were confirmed as being infected. The prevalence rate was up to 6.3% among blood donors. The East Central/South African genotype was predominantly circulating during this outbreak.
