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Increasing the availability of quality human tissue for research
Janine McCarthy1, Edward LeCluyse2, Sharon Presnell3
1Physicians Committee for Responsible Medicine, Washington, DC, USA.
ALTEX
|October 20, 2020
Summary
Researchers aim to increase the use of human tissues in research by addressing barriers in access and quality. This initiative supports the development of novel therapies and reduces reliance on animal models.
Area of Science:
- Biomedical Research
- Translational Science
- In Vitro Models
Background:
- Human tissues are crucial for understanding disease and developing therapies.
- Advances in 3D and in vitro tissue models enhance research capabilities.
- A workshop convened stakeholders to identify barriers to human tissue utilization in research.
Discussion:
- Key challenges identified include policy, scientific development, and public engagement regarding tissue provision.
- Barriers to accessing and qualifying human tissues for research need strategic solutions.
- Facilitating the availability and quality of human tissues is essential for scientific advancement.
Key Insights:
- Increased use of human tissues in research improves disease modeling and drug development.
- Addressing policy and scientific hurdles is critical for tissue accessibility.
- Public and professional education can foster greater donation and utilization of human tissues.
Outlook:
- Developing a framework for tissue donation and utilization can accelerate biomedical research.
- Enhanced access to high-quality human tissues supports the transition from animal models.
- Future initiatives aim to increase the availability and quality of human tissues for research.

