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Stoma Closure Improves Head Circumference Growth in Very Preterm Infants after Necrotizing Enterocolitis

Karina Dyrvig Honoré1, Malene Nygaard Johansen1, Lars Rasmussen2

  • 1Department of Neonatology, Odense University Hospital, Odense, Denmark.

European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [Et Al] = Zeitschrift Fur Kinderchirurgie
|October 20, 2020
PubMed

Insights

Very preterm infants (VPIs) surgically treated for necrotizing enterocolitis (NEC) show poor growth, particularly in head circumference. Growth improved after stoma closure, highlighting the impact of surgical NEC treatment on VPI development.

Area of Science:

  • Neonatal surgery
  • Pediatric growth and development
  • Gastrointestinal disorders

Background:

  • Infants born very preterm (VPIs) undergoing surgery for necrotizing enterocolitis (NEC) face risks of impaired growth.
  • Understanding long-term growth trajectories is crucial for managing these vulnerable infants.

Purpose of the Study:

  • To compare the growth of VPIs with a stoma after NEC surgery to VPIs without NEC surgery up to 6 years of age.
  • To identify specific growth patterns and potential recovery after surgical intervention for NEC.

Main Methods:

  • Retrospective cohort study of VPIs surgically treated for NEC between 2004-2008.
  • Growth data collected from medical records and parental reports.
  • Comparison group of VPIs without NEC surgery.

Main Results:

  • Nineteen VPIs with NEC and stoma survived to 6 years.
  • VPIs with NEC and stoma exhibited poorer growth compared to controls, notably in head circumference (HC).
  • HC growth velocity showed no improvement until after stoma closure (2.5-3 months corrected age).

Conclusions:

  • Surgical NEC treatment in VPIs is associated with significant growth deficits.
  • Stoma closure appears to positively influence head circumference growth in these infants.
Abstract

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