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Infrapopliteal Artery Occlusive Disease: An Overview of Vessel Preparation and Treatment Options

Srini Tummala1, Ayush Amin1, Ankit Mehta1

  • 1Department of Interventional Radiology, University of Miami Health System, Miami, FL 33136, USA.

Journal of Clinical Medicine
|October 21, 2020
PubMed

Insights

Critical limb ischemia (CLI) is a severe condition often linked to diabetes, leading to potential amputation. This review covers devices for infrapopliteal artery occlusive disease (IPOD) treatment to improve outcomes.

Area of Science:

  • Vascular Surgery
  • Endovascular Interventions
  • Diabetic Complications

Background:

  • Critical limb ischemia (CLI) signifies advanced peripheral artery disease with significant amputation risk.
  • Diabetes mellitus exacerbates CLI, often presenting as extensive multi-level infrapopliteal artery occlusive disease (IPOD).
  • Rising diabetes rates increase the prevalence of IPOD, necessitating effective treatment strategies.

Purpose of the Study:

  • To review current devices for vessel preparation (VP) in IPOD treatment.
  • To discuss strategies for optimizing outcomes in CLI patients with IPOD.
  • To enhance understanding of endovascular treatment options for infrapopliteal disease.

Main Methods:

  • Literature review of available devices for VP in IPOD.
  • Analysis of treatment strategies focusing on patency and limb salvage.
  • Synthesis of data on device efficacy and complication minimization.

Main Results:

  • Various VP devices exist to prepare infrapopliteal arteries for intervention.
  • Optimized VP is crucial for improving patency rates and wound healing.
  • Device selection impacts complication rates and long-term limb salvage.

Conclusions:

  • Effective VP is essential for successful endovascular treatment of IPOD.
  • Advances in VP devices offer improved options for CLI patients.
  • Further research into device-specific outcomes in IPOD is warranted.

Keywords:
BTK diseaseatherectomycritical limb ischemiainfrapopliteal artery diseaseperipheral artery diseasereviewtibial diseasevessel preparation

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