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Updated: Dec 5, 2025

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Published on: December 5, 2020
Metabolites from Clonostachys Fungi and Their Biological Activities
Peipei Han1, Xuping Zhang1, Dan Xu1
1Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, China.
Abstract:
Clonostachys (teleomorph: Bionectria) fungi are well known to produce a variety of secondary metabolites with various biological activities to show their pharmaceutical and agrochemical applications. Up to now, at least 229 secondary metabolites, mainly including 84 nitrogen-containing metabolites, 85 polyketides, 40 terpenoids, and 20 other metabolites, have been reported. Many of these compounds exhibit biological activities, such as cytotoxic, antimicrobial, antileishmanial, antimalarial activities. This mini-review aims to summarize the diversity of the secondary metabolites as well as their occurrences in Clonostachys fungi and biological activities.
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