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Developing core economic parameter sets for asthma studies: a realist review and an analytical framework.

Chris Roukas1, Zahidul Quayyum2, Anita Patel3

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Summary

This study identifies core economic parameters for asthma research, focusing on secondary care, primary care, medication, emergency care, and work productivity. These parameters are crucial for consistent economic evaluations in asthma interventions.

Keywords:
asthma studiescore parametershealth economics

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Area of Science:

  • Health Economics
  • Pharmacoeconomics
  • Respiratory Medicine

Background:

  • Economic evaluations are vital for assessing healthcare interventions in asthma.
  • Standardized economic parameters are needed for consistent and comparable asthma study results.
  • Previous research lacks a defined set of core economic parameters for asthma economic evaluations.

Purpose of the Study:

  • To develop a standardized core economic parameter set for economic evaluations in asthma studies.
  • To identify and categorize key economic parameters used in asthma research.
  • To provide a framework for selecting appropriate economic parameters in future asthma studies.

Main Methods:

  • Systematic literature review utilizing realist review methodology.
  • Development of an analytical framework to guide the review process.
  • Searches of multiple databases (PubMed, Cochrane, NHS EED, DARE, HTA) from 1990 onwards.

Main Results:

  • 224 publications were included from 2531 identified.
  • 65 economic parameters were identified and categorized into 11 groups.
  • Parameters related to secondary care, primary care, medication, emergency care, and work productivity constituted 84% of all identified parameters.

Conclusions:

  • Core economic parameters for asthma studies include secondary care, primary care, medication, emergency care, and work productivity.
  • Supplemental parameters such as diagnostics, healthcare delivery, school activity, informal care, medical devices, and health utility are study-specific.
  • The proposed core set enhances consistency and comparability in economic evaluations of asthma interventions.