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Related Experiment Video

Updated: Dec 5, 2025

Hierarchical and Programmable One-Pot Oligosaccharide Synthesis
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Computational tools for drawing, building and displaying carbohydrates: a visual guide.

Kanhaya Lal1,2, Rafael Bermeo1,2, Serge Perez1

  • 1Univ. Grenoble Alpes, CNRS, CERMAV, 38000 Grenoble, France.

Beilstein Journal of Organic Chemistry
|October 21, 2020
PubMed
Summary

This perspective article reviews computational tools for drawing and visualizing carbohydrate (glycan) structures. It helps researchers choose software for glycan structure representation and model building in structural glycobiology.

Keywords:
bioinformaticscarbohydrateglycanglycobiologynomenclatureoligosaccharidepolysacchariderepresentationstructure

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Area of Science:

  • Structural glycobiology
  • Computational chemistry
  • Bioinformatics

Background:

  • Drawing and visualizing molecular structures are common tasks in structural glycobiology.
  • Various software are typically used for these tasks.
  • Standardized representation of glycans and glycoconjugates is crucial for scientific communication.

Purpose of the Study:

  • To outline developments in computational tools for sketching, visualizing, and modeling glycans.
  • To provide details on the standard representation of glycans and glycoconjugates.
  • To highlight a comparative analysis of available tools for glycan structure representation and model building.

Main Methods:

  • Literature review of computational tools for glycan analysis.
  • Discussion of standard glycan representation formats.
  • Comparative analysis of software functionalities for sketching, visualization, and modeling.

Main Results:

  • An overview of current computational tools for glycan manipulation is presented.
  • Details on standard representations facilitating communication of glycan structures are provided.
  • A comparative analysis aids researchers in selecting appropriate tools for their needs.

Conclusions:

  • The reviewed computational tools can assist glycobiologists and other researchers in tasks related to glycan structure representation and model building.
  • These tools offer ready-to-use, simple programs for sketching and building glycans.
  • Effective use of these tools enhances communication and research in structural glycobiology.