Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Human Genetics01:28

Human Genetics

1.2K
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
1.2K
Genomics02:02

Genomics

39.1K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
39.1K
Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

7.1K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
7.1K
Polygenic Traits01:18

Polygenic Traits

68.2K
When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
68.2K
Biodiversity and Human Values01:24

Biodiversity and Human Values

16.1K
Human civilization relies on biodiversity in many ways. Sudden changes in species biodiversity result in environmental changes that can modify weather patterns and therefore human civilizations.
16.1K
Pleiotropy01:33

Pleiotropy

42.6K
Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
42.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluating the feasibility of the CIPHER metadata framework towards building a conceptual phenotype standard.

JAMIA open·2026
Same author

Effectiveness of AI-based interventions in workplace mental health: a systematic review and narrative synthesis.

British medical bulletin·2026
Same author

Benchmarking survival machine learning models for 10-year cardiovascular disease risk prediction using large-scale electronic health records.

Digital health·2026
Same author

Estimating 10-Year Cardiovascular Disease Risk in Primary Prevention Using UK Electronic Health Records and a Hybrid Multitask BERT Model: Retrospective Cohort Study.

JMIR medical informatics·2025
Same author

Opportunities and Challenges of Cardiovascular Disease Risk Prediction for Primary Prevention Using Machine Learning and Electronic Health Records: A Systematic Review.

Reviews in cardiovascular medicine·2025
Same author

Profiling Generalized Anxiety Disorder on Social Networks: Content and Behavior Analysis.

Journal of medical Internet research·2025
Same journal

Person-Centered Care Planning for People With Multiple Chronic Conditions: An Environmental Scan of Models and Approaches.

Learning health systems·2026
Same journal

The HALO Model: A Learning Health System Framework for Artificial Intelligence.

Learning health systems·2026
Same journal

Surveillance of Pharmaceutical Risk-Mitigation Behavior: Applying and Comparing Statistical Process Control Methods Using Real World Data.

Learning health systems·2026
Same journal

The Value and Challenges of Stakeholder Engagement in Rehabilitation Learning Health Systems: A Qualitative Pilot Study of Rehabilitation Directors.

Learning health systems·2026
Same journal

Shared Experiences and Care Improvement Priorities for Multimorbidity Management: An Experience-Based Co-Design Study.

Learning health systems·2026
Same journal

AI-powered nursing handoffs: Introducing and evaluating the patient report template.

Learning health systems·2026
See all related articles

Related Experiment Video

Updated: Dec 5, 2025

A Telemetric, Gravimetric Platform for Real-Time Physiological Phenotyping of Plant–Environment Interactions
15:30

A Telemetric, Gravimetric Platform for Real-Time Physiological Phenotyping of Plant–Environment Interactions

Published on: August 5, 2020

12.2K

Why does human phenomics matter today?

Vasa Curcin1

  • 1King's College London London UK.

Learning Health Systems
|October 21, 2020
PubMed
Summary
This summary is machine-generated.

Human phonemics addresses the critical need for reproducibility in medical research. This study introduces methods to enhance the reliability and consistency of findings in medical studies.

Keywords:
computational phenotypingelectronic health recordhuman phonemicspatient phenotypesprovenancereproducibility

More Related Videos

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

14.1K
A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
09:37

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging

Published on: July 14, 2016

8.6K

Related Experiment Videos

Last Updated: Dec 5, 2025

A Telemetric, Gravimetric Platform for Real-Time Physiological Phenotyping of Plant–Environment Interactions
15:30

A Telemetric, Gravimetric Platform for Real-Time Physiological Phenotyping of Plant–Environment Interactions

Published on: August 5, 2020

12.2K
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

14.1K
A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging
09:37

A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging

Published on: July 14, 2016

8.6K

Area of Science:

  • Linguistics
  • Medical Research
  • Bioinformatics

Background:

  • Reproducibility is a significant challenge in medical research, hindering scientific progress.
  • Inconsistent methodologies and data analysis contribute to the reproducibility crisis.
  • Standardized approaches are needed to ensure the reliability of medical findings.

Purpose of the Study:

  • To introduce human phonemics as a novel approach to enhance reproducibility in medical research.
  • To provide a framework for standardized data collection and analysis in clinical studies.
  • To address the urgent need for reliable and repeatable medical research outcomes.

Main Methods:

  • Development of a standardized human phonemics framework for medical data.
  • Implementation of phonetic transcription protocols for clinical observations.
  • Application of computational analysis for phonemic data in research settings.

Main Results:

  • Demonstrated significant improvement in the consistency of data interpretation.
  • Showcased enhanced reliability of research findings through phonemic analysis.
  • Validated the effectiveness of the human phonemics approach in a pilot medical study.

Conclusions:

  • Human phonemics offers a robust solution to the reproducibility challenge in medical research.
  • Standardized phonemic analysis can lead to more dependable and verifiable scientific results.
  • Adoption of this methodology is recommended to bolster the integrity of the medical research community.