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In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
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Non-invasive imaging of a choroidal macrovessel
Oscar Otero-Marquez1, Gerardo Ledesma-Gil1, Sharmina Alauddin1
1Department of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.
American Journal of Ophthalmology Case Reports
|October 21, 2020
Summary
A novel choroidal macrovessel, initially mistaken for a tumor, was identified using advanced non-invasive imaging. Optical coherence tomography angiography (OCTA) proved crucial in differentiating this vascular anomaly from other conditions.
Area of Science:
- Ophthalmology
- Medical Imaging
- Vascular Anatomy
Background:
- Choroidal tumors are a significant concern in ophthalmology, requiring accurate diagnosis.
- Distinguishing vascular anomalies from neoplastic lesions is critical for appropriate patient management.
Observation:
- An elevated, hypopigmented choroidal mass with a serpentine track was observed.
- Enhanced depth imaging optical coherence tomography (EDI-OCT) revealed an optically hollow lesion at the choroid-scleral junction.
- Optical coherence tomography angiography (OCTA) showed reduced flow within the lesion, and en face OCT confirmed similar reflectivity to adjacent choroidal vessels.
Findings:
- Non-invasive imaging successfully demonstrated the anatomy of a choroidal macrovessel.
- OCTA effectively differentiated the macrovessel from other potential diagnoses without dye injection.
- The study suggests a possible infra-choroidal location for this vascular variant.
Implications:
- This case highlights the utility of OCTA in diagnosing choroidal macrovessels.
- Non-invasive imaging provides a valuable alternative to traditional diagnostic methods for choroidal lesions.
- Understanding such anatomic variants improves diagnostic accuracy and patient care in ophthalmology.

