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Bromelain: A Review on its Potential as a Therapy for the Management of Covid-19

B V Owoyele1, A O Bakare2, M O Ologe3

  • 1Department of Physiology, University of Ilorin. deleyele@yahoo.com.

Nigerian Journal of Physiological Sciences : Official Publication of the Physiological Society of Nigeria
|October 21, 2020
PubMed

Insights

Bromelain shows potential for treating Coronavirus Disease 2019 (COVID-19) symptoms. Its anti-inflammatory and anticoagulatory properties may help manage severe illness progression.

Area of Science:

  • Virology
  • Immunology
  • Pharmacology

Background:

  • Coronavirus Disease 2019 (COVID-19), caused by SARS-COV-2, is a severe global health crisis.
  • High mortality rates are linked to severe inflammation and systemic coagulation.
  • Existing treatments, including repurposed drugs, have shown limited success.

Purpose of the Study:

  • To review the potential therapeutic benefits of bromelain for COVID-19 symptoms.
  • To evaluate bromelain's anti-inflammatory and anticoagulatory properties in the context of COVID-19.

Main Methods:

  • Literature review of experimental and clinical evidence.
  • Analysis of bromelain's pharmacological effects.

Main Results:

  • Bromelain exhibits significant anti-inflammatory properties.
  • Bromelain demonstrates anticoagulatory effects.
  • Evidence suggests bromelain may inhibit or prevent COVID-19 symptoms.

Conclusions:

  • Bromelain is a promising candidate for managing COVID-19 symptoms.
  • Its properties may help slow disease progression and reduce complications.
  • Further clinical investigation into bromelain for COVID-19 is warranted.

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