Detection of Bacterial and Viral Pathogens Using Photonic Point-of-Care Devices

Peuli Nath1, Alamgir Kabir1, Somaiyeh Khoubafarin Doust1

  • 1Department of Physics and Astronomy, University of Toledo, Toledo, OH 43606, USA.

Insights

Rapid point-of-care (POC) diagnostic devices offer a low-cost, portable solution for detecting infectious bacteria and viruses. These advanced technologies are revolutionizing healthcare by enabling quick, on-site testing globally.

Area of Science:

  • Biomedical Engineering
  • Infectious Disease Diagnostics
  • Nanotechnology

Background:

  • Infectious diseases caused by bacteria and viruses pose significant global health threats, necessitating rapid and accurate diagnostic methods.
  • Conventional diagnostic techniques often involve costly equipment, long wait times, and specialized personnel, limiting their accessibility, especially in resource-limited settings.
  • The emergence of pandemics like COVID-19 highlights the critical need for accessible and immediate diagnostic solutions.

Purpose of the Study:

  • To review recent advancements in novel point-of-care (POC) technologies for the rapid detection of bacterial and viral infections.
  • To highlight how these POC devices are transforming modern healthcare diagnostics.
  • To discuss the integration of plasmonics and microfluidics in developing sensitive and portable diagnostic platforms.

Main Methods:

  • Review of current literature on point-of-care diagnostic technologies.
  • Focus on plasmonics and microfluidics-based platforms for pathogen detection.
  • Integration of mobile readers and imaging systems for enhanced POC diagnostics.

Main Results:

  • POC devices based on plasmonics and microfluidics demonstrate rapid and sensitive pathogen detection capabilities.
  • These devices offer advantages such as low cost, portability, and ease of use, enabling on-site testing.
  • Recent technological breakthroughs are making POC diagnostics more accessible and effective worldwide.

Conclusions:

  • Novel point-of-care technologies are crucial for the timely diagnosis of bacterial and viral infections.
  • The development of low-cost, portable, and rapid diagnostic tools is essential for global health security.
  • These advancements represent a significant breakthrough in making infectious disease diagnostics more accessible and efficient across diverse healthcare settings.

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