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Dermatophytosis caused by Nannizzia nana
C Porras-López1, E Martínez-Herrera2, M G Frías-De-León3
1Facultad de Ciencias Químicas y Farmacia, Universidad de San Carlos de Guatemala, Guatemala; Psychodermatology task force of the Ibero-Latin American College of Dermatology (CILAD), Buenos Aires, Argentina.
Journal De Mycologie Medicale
|October 22, 2020
Summary
Nannizzia nana caused three types of tinea infections in immunocompetent Guatemalan patients. All patients recovered after treatment with Terbinafine, highlighting improved diagnostics for these fungal infections.
Area of Science:
- Medical Mycology
- Dermatology
Background:
- Dermatophytosis, fungal infections of skin, hair, and nails, can be caused by various dermatophyte species.
- Nannizzia nana is an emerging cause of human dermatophytosis.
- Accurate identification of dermatophytes is crucial for effective treatment.
Observation:
- Three immunocompetent patients in Guatemala presented with distinct tinea infections: tinea unguium, tinea pedis, and tinea cruris.
- Morphological examination revealed fungal hyphae and arthroconidia consistent with Nannizzia nana.
- Genotypic analysis, including ITS sequencing, confirmed the species identification.
Findings:
- Nannizzia nana was identified as the causative agent in all three cases.
- Phenotypic and genotypic methods successfully identified the dermatophyte species.
- All patients achieved complete recovery following Terbinafine treatment.
Implications:
- This study expands the understanding of Nannizzia nana epidemiology in human infections.
- Improved diagnostic techniques are increasing the identification of less common dermatophyte species.
- Early and accurate diagnosis of dermatophytosis leads to effective treatment and patient recovery.
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