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Localized primary breast amyloidosis and 1-year changes in imaging: A case report
Bo-Mi Kim1, Yee Jeong Kim2, Ho Hur3
1Department of Radiology, National Health Insurance Service Ilsan Hospital Goyang, 100 ilsanro, Ilsandong-gu, Goyang 10444, Korea.
Radiology Case Reports
|October 22, 2020
Summary
Localized primary breast amyloidosis, a rare benign condition, can mimic malignancies. This case highlights its mammographic and ultrasound changes over one year, emphasizing post-surgical monitoring for recurrence.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Localized primary breast amyloidosis is an exceptionally rare benign breast disease.
- It involves abnormal protein deposition within the mammary glands.
- Amyloidosis can present as a breast mass, density changes, or skin thickening, mimicking other breast pathologies.
Observation:
- A 45-year-old woman presented with a breast mass.
- Mammography and ultrasound revealed increased size and amorphous, irregular microcalcifications in the affected area over a 1-year follow-up.
- The patient was diagnosed with primary breast amyloidosis.
Findings:
- The case demonstrates the characteristic imaging evolution of primary breast amyloidosis over one year.
- Changes included mass enlargement and increased microcalcifications on mammography and ultrasound.
- These imaging findings underscore the importance of differentiating amyloidosis from malignant breast lesions.
Implications:
- Surgical resection is the current standard treatment for primary breast amyloidosis.
- Long-term patient follow-up is crucial after surgery to detect any potential recurrence.
- Understanding the imaging characteristics of breast amyloidosis aids in accurate diagnosis and management.
